Mendelian Randomization and Bayesian Colocalization Analysis Implicate Glycoprotein VI as a Potential Drug Target for Cardioembolic Stroke in South Asian Populations

Background Circulating plasma proteins are clinically useful biomarkers for stroke risk. We examined the causal links between plasma proteins and stroke risk in individuals of South Asian ancestry. Methods and Results We applied proteome‐wide Mendelian randomization and colocalization approaches to...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Siwei Wu, Devendra Meena, James Yarmolinsky, Dipender Gill, Alexander Smith, Marie‐Joe Dib, Ganesh Chauhan, Anand Rohatgi, Abbas Dehghan, Ioanna Tzoulaki
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Wiley 2024-08-01
سلاسل:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
الموضوعات:	cardioembolic GP6 Mendelian randomization South Asian ancestry stroke
الوصول للمادة أونلاين:	https://www.ahajournals.org/doi/10.1161/JAHA.124.035008
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!