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Mutant <it>pfcrt </it>"SVMNT" haplotype and wild type <it>pfmdr1 </it>"N86" are endemic in <it>Plasmodium vivax </it>dominated areas of India under high chloroquine exposure

<p>Abstract</p> <p>Background</p> <p>Chloroquine resistance (CQR) phenotype in <it>Plasmodium falciparum </it>is associated with mutations in <it>pfcrt </it>and <it>pfmdr-1 </it>genes. Mutations at amino acid position 72-76 of <it>pfcrt </it>gene, here defined as <it>pfcrt </it>haplotype are associa...

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Bibliografische Detailangaben
Hauptverfasser: Mallick Prashant K, Joshi Hema, Valecha Neena, Sharma Surya K, Eapen Alex, Bhatt Rajendra M, Srivastava Harish C, Sutton Patrick L, Dash Aditya P, Bhasin Virendra K
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2012-01-01
Schriftenreihe:Malaria Journal
Online-Zugang:http://www.malariajournal.com/content/11/1/16
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