Decreased prevalence of the Plasmodium falciparum Pfcrt K76T and Pfmdr1 and N86Y mutations post-chloroquine treatment withdrawal in Katete District, Eastern Zambia

Abstract Background In 2002, Zambia withdrew chloroquine as first-line treatment for Plasmodium falciparum malaria due to increased treatment failure and worldwide spread of chloroquine resistance. The artemisinin combination regimen, artemether–lumefantrine, replaced chloroquine (CQ) as first choic...

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Autors principals:	Mwenda C. Mulenga, Lungowe Sitali, Ilinca I. Ciubotariu, Moonga B. Hawela, Busiku Hamainza, James Chipeta, Sungano Mharakurwa
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2021-07-01
Col·lecció:	Malaria Journal
Matèries:	Chloroquine resistance Chloroquine sensitivity Malaria Mutation Genotypes
Accés en línia:	https://doi.org/10.1186/s12936-021-03859-z
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