Effects of cadherin mediated contact normalization on oncogenic Src kinase mediated gene expression and protein phosphorylation

Abstract Nontransformed cells form heterotypic cadherin junctions with adjacent transformed cells to inhibit tumor cell growth and motility. Transformed cells must override this form of growth control, called “contact normalization”, to invade and metastasize during cancer progression. Heterocellula...

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Hlavní autoři:	Rachel E. Nicoletto, Cayla J. Holdcraft, Ariel C. Yin, Edward P. Retzbach, Stephanie A. Sheehan, Amanda A. Greenspan, Christopher M. Laugier, Jason Trama, Caifeng Zhao, Haiyan Zheng, Gary S. Goldberg
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-10-01
Edice:	Scientific Reports
Témata:	Src kinase PDPN Podoplanin Contact normalization Cell transformation
On-line přístup:	https://doi.org/10.1038/s41598-024-75449-3
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