Interleukin-8 Secreted by Glioblastoma Cells Induces Microvascular Hyperpermeability Through NO Signaling Involving S-Nitrosylation of VE-Cadherin and p120 in Endothelial Cells

Glioblastoma is a highly aggressive brain tumor, characterized by the formation of dysfunctional blood vessels and a permeable endothelial barrier. S-nitrosylation, a post-translational modification, has been identified as a regulator of endothelial function. In this work we explored whether S-nitro...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Anita Guequén, Patricia Zamorano, Francisco Córdova, Tania Koning, Angelo Torres, Pamela Ehrenfeld, Mauricio P. Boric, Flavio Salazar-Onfray, Julie Gavard, Walter N. Durán, Claudia Quezada, José Sarmiento, Fabiola A. Sánchez
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-08-01
coleção:	Frontiers in Physiology
Assuntos:	adherens junction glioblastoma endothelial permeability S-nitrosylation VE-cadherin
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fphys.2019.00988/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!