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OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates

Summary: During somatic cell reprogramming to induced pluripotent stem cells (iPSCs), fibroblasts undergo dynamic molecular changes, including a mesenchymal-to-epithelial transition (MET) and gain of pluripotency; processes that are influenced by Yamanaka factor stoichiometry. For example, in early...

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Hlavní autoři: Harunobu Kagawa, Ren Shimamoto, Shin-Il Kim, Fabian Oceguera-Yanez, Takuya Yamamoto, Timm Schroeder, Knut Woltjen
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019-02-01
Edice:Stem Cell Reports
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2213671118305277
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