SorLA Controls Neurotrophic Activity by Sorting of GDNF and Its Receptors GFRα1 and RET

Glial cell-line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor that has reached clinical trials for Parkinson’s disease. GDNF binds to its coreceptor GFRα1 and signals through the transmembrane receptor tyrosine kinase RET, or RET independently through NCAM or syndecan-3. Whereas...

Descripción completa

Detalles Bibliográficos

Autores principales:	Simon Glerup, Maria Lume, Ditte Olsen, Jens R. Nyengaard, Christian B. Vaegter, Camilla Gustafsen, Erik I. Christensen, Mads Kjolby, Anders Hay-Schmidt, Dirk Bender, Peder Madsen, Mart Saarma, Anders Nykjaer, Claus M. Petersen
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2013-01-01
Colección:	Cell Reports
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S221112471200455X
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!