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SorLA Controls Neurotrophic Activity by Sorting of GDNF and Its Receptors GFRα1 and RET

Glial cell-line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor that has reached clinical trials for Parkinson’s disease. GDNF binds to its coreceptor GFRα1 and signals through the transmembrane receptor tyrosine kinase RET, or RET independently through NCAM or syndecan-3. Whereas...

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Kaydedildi:
Asıl Yazarlar: Simon Glerup, Maria Lume, Ditte Olsen, Jens R. Nyengaard, Christian B. Vaegter, Camilla Gustafsen, Erik I. Christensen, Mads Kjolby, Anders Hay-Schmidt, Dirk Bender, Peder Madsen, Mart Saarma, Anders Nykjaer, Claus M. Petersen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2013-01-01
Seri Bilgileri:Cell Reports
Online Erişim:http://www.sciencedirect.com/science/article/pii/S221112471200455X
Etiketler: Etiketle
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