Substrate recognition diversity and transport dynamics of ABCC1
Abstract ABCC1 is an ATP-binding cassette (ABC) transporter that exports diverse endogenous and exogenous substrates, conferring resistance to many anticancer drugs and mediating various physiological functions. Here, we present ten cryo-EM structures of ABCC1 in different functional states, providi...
Zapisane w:
| Główni autorzy: | , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Portfolio
2025-11-01
|
| Seria: | Nature Communications |
| Dostęp online: | https://doi.org/10.1038/s41467-025-65501-9 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|
