X-ray Crystallographic Study of Preferred Spacing by the NF-κB p50 Homodimer on κB DNA

Though originally characterized as an inactive or transcriptionally repressive factor, the NF-κB p50 homodimer has become appreciated as a physiologically relevant driver of specific target gene expression. By virtue of its low affinity for cytoplasmic IκB protein inhibitors, p50 accumulates in the...

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Principais autores:	Norman Zhu, Matthew Mealka, Shane Mitchel, Christy Milani, Lisa M. Acuña, Eric Rogers, Ashlee N. Lahana, Tom Huxford
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2023-08-01
Serija:	Biomolecules
Teme:	DNA IκBζ NF-κB protein–DNA complex p50 transcription factor
Online dostop:	https://www.mdpi.com/2218-273X/13/9/1310
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