Global phosphoproteomic study of high/low specific productivity industrially relevant mAb producing recombinant CHO cell lines

Understanding the biology of CHO cells at a cellular level is extremely valuable to the pharmaceutical industry, as it presents the opportunity to rationally engineer clonally derived cell lines (CDCLs) with elevated recombinant specific productivity (Qp). To date, relatively little is understood ab...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Laura Bryan, Michael Henry, Ronan M. Kelly, Michael Lloyd, Christopher C. Frye, Matthew D. Osborne, Martin Clynes, Paula Meleady
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2021-01-01
Colecção:	Current Research in Biotechnology
Assuntos:	Chinese hamster ovary (CHO) cells Label free quantitative proteomics Phosphoproteomics Cell specific productivity (Qp) Biopharmaceuticals
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S259026282100006X
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!