Mammosphere formation in breast carcinoma cell lines depends upon expression of E-cadherin.

Tumors are heterogeneous at the cellular level where the ability to maintain tumor growth resides in discrete cell populations. Floating sphere-forming assays are broadly used to test stem cell activity in tissues, tumors and cell lines. Spheroids are originated from a small population of cells with...

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Bibliographic Details

Main Authors:	Juan Manuel Iglesias, Izaskun Beloqui, Francisco Garcia-Garcia, Olatz Leis, Alejandro Vazquez-Martin, Arrate Eguiara, Silvia Cufi, Andres Pavon, Javier A Menendez, Joaquin Dopazo, Angel G Martin
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3790762?pdf=render
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