Alterations in the synthesis of IL-1β, TNF-α, IL-6 and their downstream targets RANKL and OPG by mouse calvarial osteoblasts in vitro: inhibition of bone resorption by cyclic mechanical strain
Mechanical strain is an important determinant of bone mass and architecture, and the aim of this investigation was to further understand the role of the cell-cell signalling molecules, IL1-β, TNF-α and IL-6 in the mechanobiology of bone. Mouse calvarial osteoblasts in monolayer culture were subjecte...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2013-10-01
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| Series: | Frontiers in Endocrinology |
| Assuntos: | |
| Acceso en liña: | http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00160/full |
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