Glucose deprivation in tuberous sclerosis complex-related tumors
<p>Abstract</p> <p>Background</p> <p>Cancer cells possess unique metabolic phenotypes that are determined by their underlying oncogenic pathways. Activation of the PI3K/Akt/mTOR signaling cascade promotes glycolysis and leads to glucose-dependence in tumors. In particular, cells with constitutive mT...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2011-10-01
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| coleção: | Cell & Bioscience |
| Assuntos: | |
| Acesso em linha: | http://www.cellandbioscience.com/content/1/1/34 |
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