DRP1 depletion protects NK cells from hypoxia-induced dysfunction

Objectives The efficacy of cellular therapies has been disappointing in solid tumors. A major barrier that contributes to the low success rate, is hypoxia within the tumor microenvironment. In this study, we investigated the influence of hypoxia on natural killer (NK) cell function and to evaluated...

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Bibliografiske detaljer

Principais autores:	Tias Verhezen, Astrid Van Den Eynde, Peter Verstraelen, Laura Gehrcken, Gabriele Palmiotto, Ho Wa Lau, Winnok H. De Vos, Sanne Van Der Heijden, Louize Brants, Jöran Melis, Jonas Van Audenaerde, Felicia Rodrigues Fortes, Maxim Le Compte, Geert Roeyen, Hans Prenen, Diana Campillo-Davo, Eva Lion, Rafael J. Argüello, Steven Van Laere, Filip Lardon, Christophe Deben, An Wouters, Evelien Smits, Jorrit De Waele
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis Group 2026-12-01
Serier:	Redox Report
Fag:	Natural killer cells Tumor microenvironment Hypoxia Mitochondria CRISPR-Cas9 ROS
Online adgang:	https://www.tandfonline.com/doi/10.1080/13510002.2026.2626181
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