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Lactate metabolism and histone lactylation in the central nervous system disorders: impacts and molecular mechanisms

Abstract Brain takes up approximately 20% of the total body oxygen and glucose consumption due to its relatively high energy demand. Glucose is one of the major sources to generate ATP, the process of which can be realized via glycolysis, oxidative phosphorylation, pentose phosphate pathways and oth...

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Autori principali: Yao Wang, Ping Li, Yuan Xu, Linyu Feng, Yongkang Fang, Guini Song, Li Xu, Zhou Zhu, Wei Wang, Qi Mei, Minjie Xie
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2024-11-01
Serie:Journal of Neuroinflammation
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Accesso online:https://doi.org/10.1186/s12974-024-03303-4
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