Myostatin Mutation Promotes Glycolysis by Increasing Phosphorylation of Phosphofructokinase via Activation of PDE5A-cGMP-PKG in Cattle Heart

Myostatin (MSTN) is a primary negative regulator of skeletal muscle mass and causes multiple metabolic changes. However, whether MSTN mutation affects heart morphology and physiology remains unclear. Myostatin mutation (MT) had no effect on cattle cardiac muscle in histological examination, but in b...

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Autors principals:	Mingjuan Gu, Xinyu Zhou, Lin Zhu, Yajie Gao, Li Gao, Chunling Bai, Lei Yang, Guangpeng Li
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-01-01
Col·lecció:	Frontiers in Cell and Developmental Biology
Matèries:	heart glycolysis PDE5A-cGMP-PKG phosphofructokinase myostatin mutation
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fcell.2021.774185/full
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