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N-3 Polyunsaturated Fatty Acid Dehydrogenase Fat-1 Regulates Mitochondrial Energy Metabolism by Altering DNA Methylation in Isolated Cells of Transgenic Cattle

The fatty acid dehydrogenase fat-1 gene, derived from Caenorhabditis elegans, encodes n-3 polyunsaturated fatty acid dehydrogenase (Δ15 desaturase) and catalyzes the 18–20-carbon n-6 polyunsaturated fatty acids (n-6 PUFA) to generate corresponding n-3 polyunsaturated fatty acids (n-3 PUFA). Subseque...

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Principais autores: Xueqiao Wang, Lin Zhu, Zhuying Wei, Mingjuan Gu, Miaomiao Yang, Xinyu Zhou, Chunling Bai, Guanghua Su, Xuefei Liu, Lei Yang, Guangpeng Li
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-04-01
Serier:Frontiers in Molecular Biosciences
Fag:
fat-1
metabolism
rate-limiting enzyme
ATP
DNA methylation
Online adgang:https://www.frontiersin.org/articles/10.3389/fmolb.2022.857491/full
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