The Volume-Regulated Anion Channel LRRC8 is Involved in the Initiation of Epidermal Differentiation and is Deregulated in Psoriasis

Recent studies have shown that LRRC8A, the essential subunit of the volume-regulated anion channel LRRC8, which is responsible for mediating cell volume regulation during hypotonic stress, is predominantly localized in the basal layer of the epidermis. This prompted us to investigate whether LRRC8A...

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Detalles Bibliográficos

Principais autores:	Magdalena Jahn, Victoria Lang, Oliver Rauh, Torsten Fauth, Claudia Buerger
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2025-05-01
Series:	JID Innovations
Assuntos:	Epidermal differentiation Keratinocytes Ion channel LRRC8 SWELL1
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S266702672500013X
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