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Estimating per-protocol effects in external comparator analyses using real-world data

Analysis of single arm trials complemented with external comparator arms (ECAs) may be used to support evidence of effectiveness of novel therapies in oncology research when a randomized trial is unavailable or unfeasible. However, the intention-to-treat effect, which is a common target of estimat...

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Autors principals: Alind Gupta, Evie Merinopoulou, Stephen J Duffield, Manuel Gomes, Seamus Kent, Nicolas Scheuer, Gerardo Machnicki, Thibaut Sanglier
Format: Artigo
Idioma:Inglês
Publicat: Becaris Publishing Limited 2025-10-01
Col·lecció:Journal of Comparative Effectiveness Research
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