Estimating per-protocol effects in external comparator analyses using real-world data

Analysis of single arm trials complemented with external comparator arms (ECAs) may be used to support evidence of effectiveness of novel therapies in oncology research when a randomized trial is unavailable or unfeasible. However, the intention-to-treat effect, which is a common target of estimat...

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Bibliografske podrobnosti

Principais autores:	Alind Gupta, Evie Merinopoulou, Stephen J Duffield, Manuel Gomes, Seamus Kent, Nicolas Scheuer, Gerardo Machnicki, Thibaut Sanglier
Format:	Artigo
Jezik:	Inglês
Izdano:	Becaris Publishing Limited 2025-10-01
Serija:	Journal of Comparative Effectiveness Research
Teme:	adherence comparative effectiveness external controls per-protocol effects target trial emulation
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