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BMS‐202, a PD‐1/PD‐L1 inhibitor, decelerates the pro‑fibrotic effects of fibroblasts derived from scar tissues via ERK and TGFβ1/Smad signaling pathways

Abstract Introduction Hypertrophic scar (HS), a fibroproliferative disorder of the skin with some tumor‐like properties, is closely related to dysregulated inflammation. PD‐1/PD‐L1 inhibitor is a promising medication for cancer therapy as its potent functions on adaptive immune response; whether it...

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Principais autores: Yuanyuan Cai, Min Xiao, Xinqing Li, Shanyu Zhou, Yangyang Sun, Wenyuan Yu, Tianlan Zhao
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2022-10-01
Serier:Immunity, Inflammation and Disease
Fag:
BMS‐202
fibroblasts
hypertrophic scar
PD‐1/PD‐L1 inhibitor
Online adgang:https://doi.org/10.1002/iid3.693
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