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18F-BMS-986229 PET imaging of tumor PD-L1 expression in glioblastoma patients

Abstract Background Neurooncologists urgently need biomarkers that can optimize the clinical development of PD-L1 targeted immunotherapy in the treatment of glioblastoma. This study evaluated PD-L1 targeted tumor imaging by positron emission tomography (PET) in glioblastoma patients, using the novel...

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Autori principali: Milan Grkovski, Mariza Daras, Tejus Bale, Serge Lyashchenko, Anne S. Reiner, Ingo K. Mellinghoff, Heiko Schöder, Mark P. S. Dunphy
Natura: Artigo
Lingua:Inglês
Pubblicazione: SpringerOpen 2025-09-01
Serie:EJNMMI Research
Soggetti:
18F-BMS-986229
PD-L1 expression
Glioblastoma
Pharmacokinetic modeling
Accesso online:https://doi.org/10.1186/s13550-025-01283-x
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