Quantifying immune-based counterselection of somatic mutations.
Somatic mutations in protein-coding regions can generate 'neoantigens' causing developing cancers to be eliminated by the immune system. Quantitative estimates of the strength of this counterselection phenomenon have been lacking. We quantified the extent to which somatic mutations are depleted in p...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science (PLoS)
2019-07-01
|
| Seri Bilgileri: | PLoS Genetics |
| Online Erişim: | https://doi.org/10.1371/journal.pgen.1008227 |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|