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CD8+ T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age

Abstract Influenza B viruses (IBVs) cause substantive morbidity and mortality, and yet immunity towards IBVs remains understudied. CD8+ T-cells provide broadly cross-reactive immunity and alleviate disease severity by recognizing conserved epitopes. Despite the IBV burden, only 18 IBV-specific T-cel...

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Principais autores: Tejas Menon, Patricia T. Illing, Priyanka Chaurasia, Hayley A. McQuilten, Chloe Shepherd, Louise C. Rowntree, Jan Petersen, Dene R. Littler, Grace Khuu, Ziyi Huang, Lilith F. Allen, Steve Rockman, Jane Crowe, Katie L. Flanagan, Linda M. Wakim, Thi H. O. Nguyen, Nicole A. Mifsud, Jamie Rossjohn, Anthony W. Purcell, Carolien E. van de Sandt, Katherine Kedzierska
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2024-04-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/s41467-024-47576-y
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