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Evaluation of an inducible knockout system in insect cells based on co-infection and CRISPR/Cas9.

Due to comparably high product titers and low production costs, the baculovirus/insect cell expression system is considered a versatile production platform in the biopharmaceutical industry. Its excellence in producing complex multimeric protein assemblies, including virus-like particles (VLPs), whi...

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Hlavní autoři: Christina Sophie Hausjell, Miriam Klausberger, Wolfgang Ernst, Reingard Grabherr
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2023-01-01
Edice:PLoS ONE
On-line přístup:https://doi.org/10.1371/journal.pone.0289178
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