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Total Syntheses of Mycolactone A/B and its Analogues for the Exploration of the Biology of Buruli Ulcer

Buruli ulcer, classified as a neglected tropical disease by the World Health Organization, is caused by a mycobacterium which secretes a macrolidic exotoxin called mycolactone A/B. In this article, several synthetic strategies for the preparation of this toxin are discussed, highlighting th...

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Hlavní autoři: Sarah Saint-Auret, Anne-Caroline Chany, Virginie Casarotto, Cédric Tresse, Lise Parmentier, Hajer Abdelkafi, Nicolas Blanchard
Médium: Artigo
Jazyk:Alemão
Vydáno: Swiss Chemical Society 2017-12-01
Edice:CHIMIA
Témata:
Buruli ulcer
Diverted total synthesis
Mycolactone
Total synthesis
On-line přístup:https://www.chimia.ch/chimia/article/view/1691
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