High serum ferritin is associated with genetic instability in myelodysplastic neoplasms

Abstract Purpose Serum ferritin is an independent prognostic marker in myelodysplastic neoplasms (MDS) and serves as a surrogate parameter for iron overload. Oxidative stress derived from iron overload may induce genomic damage, thereby promoting genetic instability and disease progression in MDS. W...

Descrición completa

Detalles Bibliográficos

Principais autores:	Christina Ganster, Hannes Treiber, Gina Westhofen, Fabian Beier, Tienush Rassaf, Haifa Kathrin Al-Ali, Reingard Stuhlmann, Bertram Glass, Ulrike Bacher, Katayoon Shirneshan, Tim H. Brümmendorf, Ulrich Germing, Norbert Gattermann, Detlef Haase
Formato:	Artigo
Idioma:	Inglês
Publicado:	Springer 2026-04-01
Series:	Journal of Cancer Research and Clinical Oncology
Assuntos:	Myelodysplastic neoplasm Iron overload Genetic instability γH2AX Telomere Serum ferritin
Acceso en liña:	https://doi.org/10.1007/s00432-026-06457-1
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!