Effects of the Cytoplasm and Mitochondrial Specific Hydroxyl Radical Scavengers TA293 and mitoTA293 in Bleomycin-Induced Pulmonary Fibrosis Model Mice

Lung fibrosis is the primary pathology in idiopathic pulmonary fibrosis and is considered to result from an increase in reactive oxygen species (ROS) levels in alveolar epithelial cells. However, the exact mechanism underlying lung fibrosis remains unclear and there is no effective therapy. The hydr...

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Bibliografische Detailangaben

Hauptverfasser:	Takahiro Sakai, Hidetsugu Takagaki, Noriyuki Yamagiwa, Michio Ui, Shinichi Hatta, Jun Imai
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2021-08-01
Schriftenreihe:	Antioxidants
Schlagworte:	hydroxyl radical cytoplasmic hydroxyl radical mitochondrial hydroxyl radical cellular senescence pulmonary fibrosis inflammation
Online-Zugang:	https://www.mdpi.com/2076-3921/10/9/1398
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