Effects of the Cytoplasm and Mitochondrial Specific Hydroxyl Radical Scavengers TA293 and mitoTA293 in Bleomycin-Induced Pulmonary Fibrosis Model Mice

Lung fibrosis is the primary pathology in idiopathic pulmonary fibrosis and is considered to result from an increase in reactive oxygen species (ROS) levels in alveolar epithelial cells. However, the exact mechanism underlying lung fibrosis remains unclear and there is no effective therapy. The hydr...

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Detalhes bibliográficos

Principais autores:	Takahiro Sakai, Hidetsugu Takagaki, Noriyuki Yamagiwa, Michio Ui, Shinichi Hatta, Jun Imai
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-08-01
coleção:	Antioxidants
Assuntos:	hydroxyl radical cytoplasmic hydroxyl radical mitochondrial hydroxyl radical cellular senescence pulmonary fibrosis inflammation
Acesso em linha:	https://www.mdpi.com/2076-3921/10/9/1398
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