Structural and functional characterization of a calcium-activated cation channel from Tsukamurella paurometabola
Tetrameric cationic channels specificity is determined by the sequence and structural conformation of their selectivity filter. Here, the authors show that a cationic channel from Tsukamurella paurometabola is non-selective due to a Ca2+-binding motif within its unusual proline-rich filter.
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2016-09-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/ncomms12753 |
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