Synthesis, antimicrobial evaluation, ADMET prediction, molecular docking and dynamics studies of pyridine and thiophene moiety-containing chalcones

In this study, three pyridine- and four thiophene-containing chalcone derivatives were synthesized via Claisen–Schmidt condensation reaction, where five derivatives were new. Different spectral analyses (IR, 1H NMR, HRMS) clarified the structures and these proposed compounds were screened for antimi...

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Bibliografske podrobnosti

Principais autores:	Fahmida Akhter, Sumita Saznin Marufa, S. M. Anyet Ullah Shohag, Hiroshi Nishino, Mohammad Sayed Alam, Md. Aminul Haque, Mohammad Mostafizur Rahman
Format:	Artigo
Jezik:	Inglês
Izdano:	The Royal Society 2025-01-01
Serija:	Royal Society Open Science
Teme:	chalcone antimicrobial activities ADMET docking molecular dynamics
Online dostop:	https://royalsocietypublishing.org/doi/10.1098/rsos.241411
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