Synthesis, antimicrobial evaluation, ADMET prediction, molecular docking and dynamics studies of pyridine and thiophene moiety-containing chalcones

In this study, three pyridine- and four thiophene-containing chalcone derivatives were synthesized via Claisen–Schmidt condensation reaction, where five derivatives were new. Different spectral analyses (IR, 1H NMR, HRMS) clarified the structures and these proposed compounds were screened for antimi...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Fahmida Akhter, Sumita Saznin Marufa, S. M. Anyet Ullah Shohag, Hiroshi Nishino, Mohammad Sayed Alam, Md. Aminul Haque, Mohammad Mostafizur Rahman
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	The Royal Society 2025-01-01
Serie:	Royal Society Open Science
Soggetti:	chalcone antimicrobial activities ADMET docking molecular dynamics
Accesso online:	https://royalsocietypublishing.org/doi/10.1098/rsos.241411
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!