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Massively parallel characterization of insulator activity across the genome

Abstract A key question in regulatory genomics is whether cis-regulatory elements (CREs) are modular elements that can function anywhere in the genome, or whether they are adapted to certain genomic locations. To distinguish between these possibilities we develop MPIRE (Massively Parallel Integrated...

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Hlavní autoři: Clarice K. Y. Hong, Yawei Wu, Alyssa A. Erickson, Jie Li, Arnold J. Federico, Barak A. Cohen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2024-09-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/s41467-024-52599-6
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