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Long noncoding RNA XIST: Mechanisms for X chromosome inactivation, roles in sex-biased diseases, and therapeutic opportunities

Sexual dimorphism has been reported in various human diseases including autoimmune diseases, neurological diseases, pulmonary arterial hypertension, and some types of cancers, although the underlying mechanisms remain poorly understood. The long noncoding RNA (lncRNA) X-inactive specific transcript...

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Bibliografische Detailangaben
Hauptverfasser: Jianjian Li, Zhe Ming, Liuyi Yang, Tingxuan Wang, Gaowen Liu, Qing Ma
Format: Artigo
Sprache:Inglês
Veröffentlicht: KeAi Communications Co., Ltd. 2022-11-01
Schriftenreihe:Genes and Diseases
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2352304222001052
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