Sirt1 decreased adipose inflammation by interacting with Akt2 and inhibiting mTOR/S6K1 pathway in mice[S]

Sirtuin type 1 (Sirt1) and protein kinase B (Akt2) are associated with development of obesity and inflammation, but the molecular mechanisms of Sirt1 and Akt2 interaction on adipose inflammation remain unclear. To explore these mechanisms, a mouse model was used. Mice were fed with a high-fat diet (...

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Detalhes bibliográficos

Principais autores:	Zhenjiang Liu, Lu Gan, Guannv Liu, Yizhe Chen, Tianjiao Wu, Fei Feng, Chao Sun
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2016-08-01
coleção:	Journal of Lipid Research
Assuntos:	sirtuin type 1 protein kinase B mammalian target of rapamycin C1 mammalian target of rapamycin/S6 kinase 1
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S002222752035210X
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