Local intra-articular injection of resveratrol delays cartilage degeneration in C57BL/6 mice by inducing autophagy via AMPK/mTOR pathway

Autophagy is an essential cellular homeostasis mechanism that was found to be compromised in aging and osteoarthritis (OA) cartilage. Previous studies showed that resveratrol can effectively regulate autophagy in other cells. The purpose of this study was to determine whether the chondroprotective e...

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Detalles Bibliográficos

Principais autores:	Na Qin, Liwei Wei, Wuyin Li, Wei Yang, Litao Cai, Zhuang Qian, Shufang Wu
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2017-07-01
Series:	Journal of Pharmacological Sciences
Assuntos:	Resveratrol Osteoarthritis Autophagy AMP activated protein kinase Mammalian target of rapamycin
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S1347861317300841
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