MEK inhibition induced downregulation of MRP1 and MRP3 expression in experimental hepatocellular carcinoma
<p>Abstract</p> <p>Background</p> <p>Hepatocellular carcinoma (HCC) exhibits strong intrinsic and acquired drug resistance which is the main obstacle to chemotherapy. Overexpression of ATP binding cassette (ABC) proteins correlates with activation of mitogen activated protein kinase (MAPK) pathway i...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2013-01-01
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| Colecção: | Cancer Cell International |
| Assuntos: | |
| Acesso em linha: | http://www.cancerci.com/content/13/1/3 |
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