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Fcγ receptor–mediated cross-linking codefines the immunostimulatory activity of anti-human CD96 antibodies

New strategies that augment T cell responses are required to broaden the therapeutic arsenal against cancer. CD96, TIGIT, and CD226 are receptors that bind to a communal ligand, CD155, and transduce either inhibitory or activating signals. The function of TIGIT and CD226 is established, whereas the...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Anne Rogel, Fathima M. Ibrahim, Stephen M. Thirdborough, Florence Renart-Depontieu, Charles N. Birts, Sarah L. Buchan, Xavier Preville, Emma V. King, Aymen Al-Shamkhani
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical investigation 2022-10-01
Saila:JCI Insight
Gaiak:
Sarrera elektronikoa:https://doi.org/10.1172/jci.insight.158444
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