Fcγ receptor–mediated cross-linking codefines the immunostimulatory activity of anti-human CD96 antibodies
New strategies that augment T cell responses are required to broaden the therapeutic arsenal against cancer. CD96, TIGIT, and CD226 are receptors that bind to a communal ligand, CD155, and transduce either inhibitory or activating signals. The function of TIGIT and CD226 is established, whereas the...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical investigation
2022-10-01
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| Series: | JCI Insight |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1172/jci.insight.158444 |
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