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Genetic and functional role of TNF-alpha in the development Trypanosoma cruzi infection.

TNF-alpha plays an important role in trypanocidal mechanisms and is related to tissue injury. This cytokine has been detected in the heart of human chagasic patients where it is associated with tissue damage. This study investigated whether TNF-alpha levels and the presence of genetic polymorphisms...

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Autors principals: Cristina Wide Pissetti, Dalmo Correia, Rafael Faria de Oliveira, Maurício Manoel Llaguno, Marly Aparecida Spadotto Balarin, Roseane Lopes Silva-Grecco, Virmondes Rodrigues
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2011-01-01
Col·lecció:PLoS Neglected Tropical Diseases
Accés en línia:http://europepmc.org/articles/PMC3050938?pdf=render
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