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Stability of blood‐based biomarkers of Alzheimer's disease over multiple freeze‐thaw cycles

Abstract Introduction Freeze‐thaw instability may contribute to preanalytical variation in blood‐based biomarker studies. We investigated the effects of up to four freeze‐thaw cycles on single molecule array immunoassays of serum neurofilament light chain and plasma total tau, amyloid β 1–40 (Aß40),...

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Principais autores: Ashvini Keshavan, Amanda Heslegrave, Henrik Zetterberg, Jonathan M. Schott
Format: Artigo
Jezik:Inglês
Izdano: Wiley 2018-01-01
Serija:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
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Online dostop:https://doi.org/10.1016/j.dadm.2018.06.001
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