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A Roadmap for the Molecular Farming of Viral Glycoprotein Vaccines: Engineering Glycosylation and Glycosylation-Directed Folding

Immunization with recombinant glycoprotein-based vaccines is a promising approach to induce protective immunity against viruses. However, the complex biosynthetic maturation requirements of these glycoproteins typically necessitate their production in mammalian cells to support their folding and pos...

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Principais autores: Emmanuel Margolin, Max Crispin, Ann Meyers, Ros Chapman, Edward P. Rybicki
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-12-01
Colecção:Frontiers in Plant Science
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fpls.2020.609207/full
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