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A Roadmap for the Molecular Farming of Viral Glycoprotein Vaccines: Engineering Glycosylation and Glycosylation-Directed Folding

Immunization with recombinant glycoprotein-based vaccines is a promising approach to induce protective immunity against viruses. However, the complex biosynthetic maturation requirements of these glycoproteins typically necessitate their production in mammalian cells to support their folding and pos...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Emmanuel Margolin, Max Crispin, Ann Meyers, Ros Chapman, Edward P. Rybicki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020-12-01
Schriftenreihe:Frontiers in Plant Science
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fpls.2020.609207/full
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