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Acetylation of H3K115 is associated with fragile nucleosomes at CpG island promoters and active regulatory sites

Acetylation of lysine residues in the tail domain of histone H3 is well characterised, but lysine residues in the histone globular domain are also acetylated. Histone modifications in the globular domain have regulatory potential because of their impact on nucleosome stability but remain poorly char...

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Principais autores: Yatendra Kumar, Dipta Sengupta, Elias T Friman, Robert S Illingworth, Manon Soleil, Zheng Fan, Hua Wang, Kristian Helin, Matthieu Gérard, Wendy A Bickmore
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications Ltd 2026-03-01
Series:eLife
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Acceso en liña:https://elifesciences.org/articles/108802
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