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DNA methylation directs genomic localization of Mbd2 and Mbd3 in embryonic stem cells

Cytosine methylation is an epigenetic and regulatory mark that functions in part through recruitment of chromatin remodeling complexes containing methyl-CpG binding domain (MBD) proteins. Two MBD proteins, Mbd2 and Mbd3, were previously shown to bind methylated or hydroxymethylated DNA, respectively...

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Hlavní autoři: Sarah J Hainer, Kurtis N McCannell, Jun Yu, Ly-Sha Ee, Lihua J Zhu, Oliver J Rando, Thomas G Fazzio
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications Ltd 2016-11-01
Edice:eLife
Témata:
On-line přístup:https://elifesciences.org/articles/21964
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