Electroacupuncture alleviates myocardial ischemia-reperfusion injury by targeting and inhibiting NLRP3 inflammasome-mediated cardiomyocyte pyroptosis via serum exosomal miR-22-3p

BackgroundMyocardial ischemia-reperfusion injury (MIRI) presents a significant challenge to the effectiveness of reperfusion therapy in severe ischemic heart disease. One of the core pathological mechanisms of MIRI is NLRP3 inflammasome-mediated cardiomyocyte pyroptosis. While electroacupuncture (EA...

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Autors principals:	Jian Xiong, Ying Wei, Yunnan Liu, Fayang Ling, Yi Zhao, Yu Liu, Yuxin Sun, Dehua Li, Mingsheng Sun, Dingjun Cai, Wenchuan Qi, Qianhua Zheng, Fanrong Liang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-06-01
Col·lecció:	Frontiers in Immunology
Matèries:	electroacupuncture exosomes miR-22-3p myocardial ischemia reperfusion injury NLRP3 pyroptosis
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1824799/full
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