Electroacupuncture alleviates myocardial ischemia-reperfusion injury by targeting and inhibiting NLRP3 inflammasome-mediated cardiomyocyte pyroptosis via serum exosomal miR-22-3p

BackgroundMyocardial ischemia-reperfusion injury (MIRI) presents a significant challenge to the effectiveness of reperfusion therapy in severe ischemic heart disease. One of the core pathological mechanisms of MIRI is NLRP3 inflammasome-mediated cardiomyocyte pyroptosis. While electroacupuncture (EA...

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Hlavní autoři:	Jian Xiong, Ying Wei, Yunnan Liu, Fayang Ling, Yi Zhao, Yu Liu, Yuxin Sun, Dehua Li, Mingsheng Sun, Dingjun Cai, Wenchuan Qi, Qianhua Zheng, Fanrong Liang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-06-01
Edice:	Frontiers in Immunology
Témata:	electroacupuncture exosomes miR-22-3p myocardial ischemia reperfusion injury NLRP3 pyroptosis
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1824799/full
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