(1<i>R</i>,2<i>R</i>,3<i>S</i>,4<i>R</i>)-1-(Acetylamino)-2,4,5-tris(acetyloxy)-1-((2<i>S</i>)-4-(benzyloxy)-5-oxo-2,5-dihydrofuran-2-yl)pentan-3-yl Acetate

Treatment of <i>N</i>-acetylneuraminic acid with excess base in the presence of benzyl bromide gives a polyhydroxylated 1,4 lactone which after acetylation gave the title compound in 20% overall yield. The structure of the product was confirmed by single crystal X-ray diffraction analysis, as well a...

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Hauptverfasser:	Liam S. Fitzgerald, Ciaran O’Malley, Paul V. Murphy
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-02-01
Schriftenreihe:	Molbank
Schlagworte:	sialic acid N-acetylneuraminic acid 1,4 lactones γ-lactones polyhydroxylated compounds
Online-Zugang:	https://www.mdpi.com/1422-8599/2022/1/M1337
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