Lewis Acid-Catalyzed 2,3-Dihydrofuran Acetal Ring-Opening Benzannulations toward Functionalized 1-Hydroxycarbazoles

The development of a Lewis acid-catalyzed, intramolecular ring-opening benzannulation of 5-(indolyl)2,3-dihydrofuran acetals is described. The resulting 1-hydroxycarbazole-2-carboxylates are formed in up to 90% yield in 1 h. The dihydrofuran acetals are readily accessed from the reactions of enol et...

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Detalhes bibliográficos

Principais autores:	Shaoren Yuan, Gabriel Guerra Faura, Hailey E. Areheart, Natalie E. Peulen, Stefan France
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-11-01
coleção:	Molecules
Assuntos:	benzannulation carbazoles dihydrofuran acetals ring-opening cyclizations synthetic methods
Acesso em linha:	https://www.mdpi.com/1420-3049/27/23/8344
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